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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ADAM15 All Species: 19.7
Human Site: T63 Identified Species: 54.17
UniProt: Q13444 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13444 NP_003806.3 814 87717 T63 S L K K V L Q T S L P E P L R
Chimpanzee Pan troglodytes XP_513846 831 89236 T80 S L K K V L Q T S L P E P L R
Rhesus Macaque Macaca mulatta XP_001112574 775 83647 T63 S L K K V L Q T S L P E P L R
Dog Lupus familis XP_865076 843 90172 T63 S L A E M L Q T N L P E A F R
Cat Felis silvestris
Mouse Mus musculus O88839 864 92645 T64 S L A D V L Q T G L P E A L R
Rat Rattus norvegicus Q9QYV0 816 88034 T64 N L T E V L Q T G L P E T L R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001136322 922 101009 K80 P A N S I Y S K N H P S L L Q
Frog Xenopus laevis O42596 935 104143 L85 S P Q H Q D Q L T H V A Q A S
Zebra Danio Brachydanio rerio XP_001335318 961 104960 I53 T P Q P D A R I T H S S H N V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.7 86.4 79 N.A. 75.8 81.6 N.A. N.A. 36.6 28.2 34.6 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 97.4 87.5 85.6 N.A. 82.7 87.9 N.A. N.A. 51.9 43.3 47.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 60 N.A. 73.3 66.6 N.A. N.A. 13.3 13.3 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 80 N.A. 73.3 80 N.A. N.A. 33.3 26.6 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 12 23 0 0 12 0 0 0 0 0 12 23 12 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 12 12 12 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 23 0 0 0 0 0 0 0 67 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 % F
% Gly: 0 0 0 0 0 0 0 0 23 0 0 0 0 0 0 % G
% His: 0 0 0 12 0 0 0 0 0 34 0 0 12 0 0 % H
% Ile: 0 0 0 0 12 0 0 12 0 0 0 0 0 0 0 % I
% Lys: 0 0 34 34 0 0 0 12 0 0 0 0 0 0 0 % K
% Leu: 0 67 0 0 0 67 0 12 0 67 0 0 12 67 0 % L
% Met: 0 0 0 0 12 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 12 0 12 0 0 0 0 0 23 0 0 0 0 12 0 % N
% Pro: 12 23 0 12 0 0 0 0 0 0 78 0 34 0 0 % P
% Gln: 0 0 23 0 12 0 78 0 0 0 0 0 12 0 12 % Q
% Arg: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 67 % R
% Ser: 67 0 0 12 0 0 12 0 34 0 12 23 0 0 12 % S
% Thr: 12 0 12 0 0 0 0 67 23 0 0 0 12 0 0 % T
% Val: 0 0 0 0 56 0 0 0 0 0 12 0 0 0 12 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _